Joint Rehab Science
How Does Joint Rehab™ Work?
Both cetylated fatty acids and creatine monohydrate have been reported to have potential anti-inflammatory properties and/or activity in scientific literature. (Diehl and May 1994; Hesslink, et al. 2002).
For example, cetylated fatty acids have been shown to have the ability to reduce inflammation in various joint/ligament regions of test animals, and knee/ligament areas in humans. However the mechanism by which this is accomplished in man is as yet unknown. It may possibly be acting in one of the following ways; as a biological “dampener” in which there is a type of (a)“physical removal” of the pro-inflammatory molecules, (b) an inhibitor of pro-inflammatory molecule by “sitting on” or in some way ”blocking” cell membrane sites that the inflammatory molecules would use.
Additionally, creatine supplementation has been shown to influence cell permeability and cell surface reactivity. When both (or either) creatine, or the high energy form phosphorylated creatine, build up inside a cell, they may reduce inflammation by potentially interfering with or blocking one or more inflammatory promoting molecules from reaching their receptor site on the cell wall. In vitro endothelial cell adhesion experiments demonstrated that, as creatine or the phosphorylated creatine concentrations increased, cell surface adhesion and permeability were both modified.